The main concern associated with antiepileptic drugs in pregnancy consists of maternal and fetal risks. There is still uncertainty concerning the risk of fetal malformation associated with intake of various antiepileptic drugs, especially the newer agents, in pregnancy. We want to know what the situation is in the province of Quebec.

Through this study, we aim to determine the prevalence and trends of anti-epileptic drugs use during pregnancy and to evaluate their association with major congenital malformations. Dosage, type of medication and drug combinations are considered. These aspects of anti-epileptic medication use during pregnancy are studied using data from the Quebec Pregnancy Registry.

Funding source
Fonds de la Recherche en Santé du Québec (FRSQ), Réseau Québécois de Recherche sur l'Usage des Médicaments (RQRUM), Réseau FRSQ pour le bien-être des enfants.