Cohorts and sources of data

A North American field study on antidepressants: Mother's health and development of the child.
In order to achieve epidemiologic studies about antidepressants use in the perinatal period and cognitive and behavioural development of the child, a multicentric prospective cohort study is presently conducted in order to recruit a group of 300 pregnant women using antidepressants at the time of the pregnancy diagnosis, and another group of 100 women taking no antidepressants during pregnancy.

Pregnant women are recruited when their health professional or the woman herself calls one of the major North American teratology information services :

a)	IMAGe Center, CHU de Sainte-Justine, Montreal, Canada
b)	Motherisk, Hospital for sick children, Toronto, Canada
c)	FRAME Children's Hospital of Western Ontario, London, Canada
d)	OTIS (Organisation of Teratology Information Specialists), USA

Pregnant women can also contact us directly by phone or email.

Information on the severity of depression and anxiety, lifestyle, perinatal complications, health care system utilization, quality of life, pre and postpartum maternal stress, as well as maternal attachment is collected using telephone interviews during the 1st, 2nd, and 3rd trimester of pregnancy, as well as 2 and 12 months after the delivery. Furthermore, children are evaluated at home by a cognitive development specialist at 12 months of age.

Ethics approval was obtained from CHU Sainte-Justine, Sick Kids Hospital, and West Ontarian Hospital for children ethics committees.

Funding source
Canadian Institutes of Health Research (CIHR), Fonds de la recherche en santé du Québec (FRSQ), and Conseil du Médicament.

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